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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 1
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2008 13
2009 18
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2014 24
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336 results

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Page 1
Stanniocalcin 1 is a phagocytosis checkpoint driving tumor immune resistance.
Lin H, Kryczek I, Li S, Green MD, Ali A, Hamasha R, Wei S, Vatan L, Szeliga W, Grove S, Li X, Li J, Wang W, Yan Y, Choi JE, Li G, Bian Y, Xu Y, Zhou J, Yu J, Xia H, Wang W, Alva A, Chinnaiyan AM, Cieslik M, Zou W. Lin H, et al. Cancer Cell. 2021 Apr 12;39(4):480-493.e6. doi: 10.1016/j.ccell.2020.12.023. Epub 2021 Jan 28. Cancer Cell. 2021. PMID: 33513345 Free PMC article.
However, therapeutic resistance poses a major challenge to current immunotherapies. Here, we identify that expression of tumor stanniocalcin 1 (STC1) correlates with immunotherapy efficacy and is negatively associated with patient survival across diverse canc …
However, therapeutic resistance poses a major challenge to current immunotherapies. Here, we identify that expression of tumor stanniocal …
Stanniocalcin 1 promotes metastasis, lipid metabolism and cisplatin chemoresistance via the FOXC2/ITGB6 signaling axis in ovarian cancer.
Lin F, Li X, Wang X, Sun H, Wang Z, Wang X. Lin F, et al. J Exp Clin Cancer Res. 2022 Apr 7;41(1):129. doi: 10.1186/s13046-022-02315-3. J Exp Clin Cancer Res. 2022. PMID: 35392966 Free PMC article.
BACKGROUND: Stanniocalcin 1 (STC1) plays an integral role in ovarian cancer (OC). ...Moreover, STC1 was directly regulated by Forkhead box C2 (FOXC2) in OC. Notably, targeting STC1 and the FOXC2/ITGB6 signaling axis was related to DDP chemoresis …
BACKGROUND: Stanniocalcin 1 (STC1) plays an integral role in ovarian cancer (OC). ...Moreover, STC1 was directly …
Stanniocalcin 1 promotes lung metastasis of breast cancer by enhancing EGFR-ERK-S100A4 signaling.
Liu A, Li Y, Lu S, Cai C, Zou F, Meng X. Liu A, et al. Cell Death Dis. 2023 Jul 4;14(7):395. doi: 10.1038/s41419-023-05911-z. Cell Death Dis. 2023. PMID: 37400459 Free PMC article.
Tumor secretory factors are important mediators for the adaptation of cancer cells to foreign microenvironments. Here, we report that tumor-secreted stanniocalcin 1 (STC1) promotes the pulmonary metastasis of breast cancer by enhancing the invasiveness of tum …
Tumor secretory factors are important mediators for the adaptation of cancer cells to foreign microenvironments. Here, we report that tumor- …
Stanniocalcin-1 Promotes PARP1-Dependent Cell Death via JNK Activation in Colitis.
Zhu L, Xie Z, Yang G, Zhou G, Li L, Zhang S. Zhu L, et al. Adv Sci (Weinh). 2024 Feb;11(5):e2304123. doi: 10.1002/advs.202304123. Epub 2023 Dec 13. Adv Sci (Weinh). 2024. PMID: 38088577 Free PMC article.
Stanniocalcin-1 (STC1) is upregulated by inflammation and modulates oxidative stress-induced cell death. Herein, the function of STC1 in colitis and stress-induced parthanatos, a newly identified type of programmed necrotic cell death dependent on the …
Stanniocalcin-1 (STC1) is upregulated by inflammation and modulates oxidative stress-induced cell death. Herein, the fu …
A proteomic atlas of senescence-associated secretomes for aging biomarker development.
Basisty N, Kale A, Jeon OH, Kuehnemann C, Payne T, Rao C, Holtz A, Shah S, Sharma V, Ferrucci L, Campisi J, Schilling B. Basisty N, et al. PLoS Biol. 2020 Jan 16;18(1):e3000599. doi: 10.1371/journal.pbio.3000599. eCollection 2020 Jan. PLoS Biol. 2020. PMID: 31945054 Free PMC article.
Our analyses identify several candidate biomarkers of cellular senescence that overlap with aging markers in human plasma, including Growth/differentiation factor 15 (GDF15), stanniocalcin 1 (STC1), and serine protease inhibitors (SERPINs), which significantl …
Our analyses identify several candidate biomarkers of cellular senescence that overlap with aging markers in human plasma, including Growth/ …
Myriad Functions of Stanniocalcin-1 (STC1) Cover Multiple Therapeutic Targets in the Complicated Pathogenesis of Idiopathic Pulmonary Fibrosis (IPF).
Ohkouchi S, Ono M, Kobayashi M, Hirano T, Tojo Y, Hisata S, Ichinose M, Irokawa T, Ogawa H, Kurosawa H. Ohkouchi S, et al. Clin Med Insights Circ Respir Pulm Med. 2015 Dec 29;9(Suppl 1):91-6. doi: 10.4137/CCRPM.S23285. eCollection 2015. Clin Med Insights Circ Respir Pulm Med. 2015. PMID: 26740747 Free PMC article. Review.
These facts point out the necessity of using a combination of drugs, that is, each single drug with molecular targets or a single drug with multiple therapeutic targets. In this review, we introduce a humoral factor, stanniocalcin-1 (STC1), which has myriad f …
These facts point out the necessity of using a combination of drugs, that is, each single drug with molecular targets or a single drug with …
Role of stanniocalcin-1 in breast cancer.
Chen F, Zhang Z, Pu F. Chen F, et al. Oncol Lett. 2019 Oct;18(4):3946-3953. doi: 10.3892/ol.2019.10777. Epub 2019 Aug 22. Oncol Lett. 2019. PMID: 31579413 Free PMC article. Review.
Breast cancer is a highly heterogeneous disease consisting of five disease subtypes with distinct histological characteristics, clinical behaviors and prognostic features. Stanniocalcin-1 (STC1) is a secreted glycoprotein hormone that has been demonstrated to …
Breast cancer is a highly heterogeneous disease consisting of five disease subtypes with distinct histological characteristics, clinical beh …
Stanniocalcin-1 in the female reproductive system and pregnancy.
Bishop A, Cartwright JE, Whitley GS. Bishop A, et al. Hum Reprod Update. 2021 Oct 18;27(6):1098-1114. doi: 10.1093/humupd/dmab028. Hum Reprod Update. 2021. PMID: 34432025 Free PMC article. Review.
BACKGROUND: Stanniocalcin-1 (STC-1) is a widely expressed glycoprotein hormone involved in a diverse spectrum of physiological and pathophysiological processes including angiogenesis, mineral homeostasis, cell proliferation, inflammation and apoptosis. ...SEA …
BACKGROUND: Stanniocalcin-1 (STC-1) is a widely expressed glycoprotein hormone involved in a diverse spectrum of physio …
Stanniocalcin-1 is a Modifier of Oxygen-Induced Retinopathy Severity.
Dalvin LA, Hartnett ME, Bretz CA, Hann CR, Cui RZ, Marmorstein AD, Sheikh-Hamad D, Fautsch MP, Roddy GW. Dalvin LA, et al. Curr Eye Res. 2020 Jan;45(1):46-51. doi: 10.1080/02713683.2019.1645184. Epub 2019 Aug 28. Curr Eye Res. 2020. PMID: 31314602 Free PMC article.
However, these therapies have side effects, and even with adequate treatment, visual acuity can be impaired. Novel therapeutic options are needed. Stanniocalcin-1 (STC-1) is a neuroprotective protein with anti-inflammatory and anti-oxidative stress properties …
However, these therapies have side effects, and even with adequate treatment, visual acuity can be impaired. Novel therapeutic options are n …
The stromal-tumor amplifying STC1-Notch1 feedforward signal promotes the stemness of hepatocellular carcinoma.
Bai S, Zhao Y, Chen W, Peng W, Wang Y, Xiong S, Aruna, Li Y, Yang Y, Chen S, Cheng B, Wang R. Bai S, et al. J Transl Med. 2023 Mar 31;21(1):236. doi: 10.1186/s12967-023-04085-8. J Transl Med. 2023. PMID: 37004088 Free PMC article.
BACKGROUND: Cancer-associated fibroblasts (CAFs), an important component of the tumor microenvironment (TME), play crucial roles in tumor stemness. It has been shown in various cancer studies that stanniocalcin-1 (STC1) is secreted by CAFs, however, its funct …
BACKGROUND: Cancer-associated fibroblasts (CAFs), an important component of the tumor microenvironment (TME), play crucial roles in tumor st …
336 results